The Mouse anti Human Interleukin-32:Biotin Antibody from MyBioSource.com is a Mouse Monoclonal antibody to IL32, and Interleukin 32. This antibody recognizes Human antigen. The Mouse anti Human Interleukin-32:Biotin Antibody has been validated for the following applications: EIA, Immunoassay, and ELISA.
Description
Mouse anti Human interleukin-32 antibody, clone B01-2A7, recognizes interleukin-32 (IL-32), also known as NK4 and TAIF. IL-32 is a pro-inflammatory cytokine with roles in inflammation and immune regulation, and its expression is strongly regulated by pathogens and pro-inflammatory cytokines (Hong et al. 2017). IL-32 promotes inflammation by upregulating other inflammatory cytokines including TNF-alpha, IL-1beta, IL-6, INF-gamma, and IL-8 (Al-Shobaili et al. 2018). Accordingly, a role for IL-32 has been reported in the pathogenesis of chronic inflammatory diseases including IBD, COPD and RA (Damen et al. 2017). IL-32 is highly expressed in several cancer tissues, and plays a crucial role in cancer development through tumor initiation, cell proliferation, and tumor maintenance (Yan et al. 2018).
The biotinylated Mouse anti Human interleukin-32 antibody, clone B01-2A7 can be used as a detection antibody in a sandwich ELISA with the purified Mouse anti Human interleukin-32 antibody, clone E03-4C9 as the capture antibody